Treatment of bacterial infections:
-Adults:250 mg twice daily for 8 days. Continue treatment with ciprofloxacin (cipro) (500 mg every 12 hours) for bacterial infection in patients 18 years and older. Continue for other infections as prescribed. See package insert for specific directions on use.
Dosage varies by infection. In critically ill patients or patients with severe burns, and in patients with septicemia, or in patients with aplastic '.', and in patients with or with aplastic '.', are recommended in the following categories:
The usual dose for bacterial infections is one or two 500 mg tablets taken as a single dose (500 mg to 1,500 mg/72 hours) or as a two-pack (500 mg to 1,500 mg/28 hours).
Dosage may be adjusted on the basis of culture and bacteriological results. Seesection.
Dizziness or lightheadedness may occur as a side effect of Ciprofloxacin.izziewise that dizziness or lightheadedness may occur as a side effect of ciprofloxacin. NOTE: These side effects are rare and may occur. If the side effects are severe and persist for a longer duration, contact your doctor or pharmacist.
Do not take ciprofloxacin if:
- Patients with following conditions:
- Hepatic impairment (over 30%).
- Severe renal or severe hepatic failure, including severe severe renal insufficiency.
- Patient may become yellowing of skin or eyes (3).
- Hypersensitivity (4)
- Drug reaction with eosinophils: possible with dose-related side effects.
- Patient may have joint pain or swelling, rash or fever. If rash, greater frequency with higher doses.
- If vomiting occurs, contact your doctor or pharmacist.
- If the skin rash becomes severe or lingers for longer than 3 days, seek medical help immediately.
- Other infections:
- Severe infection: severe bacteriuria (see package insert for specific directions on use)
- Skin reaction within first few days of therapy: e.g. rash, itching, new mild or moderate symptoms, evidence of infection. Continue to take the drug as prescribed.
- Drug-drug hypersensitivity: use with extreme caution.
- Hepatic impairment: consider 60 mg/kg/72 hour (5 mL) of ciprofloxacin (cipro). NOTE: hepatic insufficiency is expected in patients less than 30 kg. Note: patient with severe renal impairment.
- Renal and hepatic dysfunction: use with extreme caution. See package insert for specific details.
- Severe infections: patient may develop confusion, or confusion, with acute renal failure. See insert for specific details.
DESCRIPTION:Ciprofloxacin, a synthetic, broad spectrum antibiotic from the fluoroquinolone class, is used to treat a variety of bacterial infections including and.
Active ingredient:Ciprofloxacin hydrochloride
Inactive ingredients:Ciprofloxacin trihydrate (e.g. triethyl citrate), isobutylhydroxytoluene (e.g. tetrahydrofused hydroperoxide) and polyethylene glycol (e.g. polydextrose).
Pharmaceutical properties:Dosage form, dosage form, formulation.
Pharmaceutical dosage form:Film-coated tablets.
Pharmaceutical formulation:Tablet, film-coated tablets, tablet, film-coated vials.
Manufacturer:AstraZeneca
Distributed by:
Source:MedExpress, Inc.
Product expiry date:March 31, 2023
Product name: Ciprofloxacin tablets
Dosage form:Film-coated tablet, tablet, film-coated tablet, film-coated tablet, vials
Package size:10 x 10 tablets, vials
Available size:4 x 4 x 4 tablets
Possible side effects:Nausea, stomach upset, vomiting, metallic taste in the mouth, or allergic reactions.
Interactions:Alcohol, medicines containing phenazolamide, carbamazepine, phenytoin, thioridazine, thioridazine derivatives.
Warnings:Use with caution in patients with liver disease, severe renal impairment, severe hepatic failure, severe drug-induced hypoglycemia, or who have a history of hypersensitivity.
Inform your doctor if you have ever had: severe hypersensitivity, severe diarrhea, skin rash, jaundice, liver impairment, or a history of peptic ulcer disease. If these conditions cause pain or fever, stop use immediately. Stop use immediately if you experience any of these symptoms. If the patient is pregnant, trying to become pregnant, or breastfeeding, tell your doctor before taking this medication.
Avoid alcohol when taking this medication and for at least 48 hours after stopping it. Drinking alcohol while taking ciprofloxacin can make you more sensitive to the side effects of ciprofloxacin.
Precautions:Before taking ciprofloxacin, tell your doctor or pharmacist if you are allergic to it or to any other quinolone or fluoroquinolone antibiotics (e.g. levofloxacin, moxifloxacin); or if you have any of the following medical conditions: heart disease, irregular heartbeat, angina, liver disease, kidney disease, low blood pressure, diabetes, seizure disorder, or a history of an acute myocardial infarction (ascorbic acid-induced). If your doctor decides to use ciprofloxacin for an infection, do not stop using the medication without doctor's advice. The risk of side effects is increased when the drug is taken with alcohol.
Avoid using this medication if you are pregnant or breastfeeding and your doctor has judged that the benefit to you is greater than the risk of side effects. Tell your doctor if you are pregnant or plan to become pregnant.
Keep out of reach of children. Ciprofloxacin is excreted in breast milk. Consult your doctor before breast-feed if you are pregnant or planning to have a baby. Consult your doctor before breast-feed if you are pregnant.
Ciprofloxacin should be used with caution in patients with liver disease, severe renal impairment, severe drug-induced hypoglycemia, or who have a history of hypersensitivity. If you experience any of these symptoms, stop using ciprofloxacin and call your doctor immediately. Do not use this medication without first talking to your doctor.
Introduction:The antibiotic Ciprofloxacin has been used for over two decades in the treatment of bacterial infections. However, its use is increasing in the context of the world’s prevalence of antibiotic resistance. Ciprofloxacin is a broad-spectrum antibiotic, with a broad spectrum of activity against Gram-positive bacteria and a high selectivity for Gram-negative bacteria. The drug has a high selectivity for Gram-positive bacteria, such as Escherichia coli, and has a high selectivity for Gram-negative bacteria such as Salmonella and Clostridium species, but it is less effective against Enterococcus faecium and E. coli.
Background:The antibiotic Ciprofloxacin is a broad-spectrum antibiotic. Its ability to inhibit the replication of several Gram-positive and Gram-negative bacteria makes it useful for infections caused by microorganisms that have already been exposed to a broad spectrum of antibiotics.
Methods:The aim of this study was to evaluate the use of Ciprofloxacin and its metabolites in the treatment of patients with bacterial infections, to assess the effects of the drug on other microorganisms and to compare the efficacy of the drugs in the treatment of other infections.
A total of 60 patients with bacterial infections of the respiratory tract were studied. The patients were divided into two groups according to their severity of illness: patients with a bacterial infection of the spleen, who were treated with Ciprofloxacin and patients who were treated with other drugs. The two groups were compared using a computerized analysis of variance test, and the difference in the concentrations of Ciprofloxacin, which is the antibiotic metabolite, was calculated by the formula:
Results:The mean concentrations of the drug in the two groups were significantly lower than those in the control group. The results of the calculations showed that the drug could significantly reduce the concentrations of the drug. The maximum values of the concentration of Ciprofloxacin were observed in the group treated with Ciprofloxacin. The maximum values of the concentration of Ciprofloxacin in the other group were significantly lower than those in the group treated with other drugs.
Conclusions:The use of Ciprofloxacin is considered as a good option for the treatment of bacterial infections of the spleen, which was significantly lower than the use of other antibiotics in patients with bacterial infections of the spleen. The results suggest that the use of Ciprofloxacin may be useful in reducing the levels of Ciprofloxacin in the body.
IMPORTANT SAFETY, EFFECTS, AND EFFECTSThe use of antibiotics to treat bacterial infections is a common concern in the world. The World Health Organization has listed the risk of developing various health problems associated with the use of antibiotics, and in particular Ciprofloxacin, as one of the leading risk factors in bacterial infections. This is especially true for the treatment of infections caused by bacteria that have already been exposed to a broad spectrum of antibiotics, such as those that are the focus of the present study. The use of antibiotics, particularly in the treatment of bacterial infections, is a major risk factor for the development of antibiotic-resistant bacterial strains. It is estimated that more than 3.2 million Americans in the United States are living with the spread of antibiotic-resistant bacteria, and that approximately 5.4% of Americans are living with these bacteria. In addition, the prevalence of antibiotic-resistant bacteria increases with the number of antibiotic-resistant bacteria strains and the age of the population. Therefore, it is important to identify the most suitable antibiotic for the treatment of bacterial infections in order to reduce the risk of antibiotic-resistant bacterial strains.
REFERENCES1
Tong, R. E., C. E. et al. The Effect of Ciprofloxacin on the Activity of Aminoglycoside Antibiotics: A Review. Infection. 2004;53(4):847-53..2The authors declare no conflicts of interest.
Ciprofloxacin is a generic name for the antibiotic ciprofloxacin hydrochloride. The product is marketed under the brand name Cipro®.
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